Submitted by Dr.Kattlove’s Cancer Blog

“Senator Kennedy, you have a malignant brain tumor called glioblastoma, which set off the seizures you had the other day. Although we can see a tumor on the MRI, there is more there than we can see. Along with the mass in the front of your brain, we know from years of experience in dealing with these that there are little fingers of cancer extending from this tumor into the rest of your brain.

“How does this affect your treatment? Surgery cannot remove the cancer entirely. Although we can remove most of your tumor with surgery, we can’t cure you. Sometimes the surgery can help prevent some symptoms like headaches. But, with surgery, you may lose some normal functions, like speech and perhaps even understanding. And, although the seizures can be troublesome, they can be controlled with medication.

“Many patients in your situation will undergo radiation therapy along with a drug called temozolomide. Studies have shown that this will extend your life by a few months. But, you should know that most people with your condition, especially at your age, survive less than a year even with the most aggressive treatment.

“And you should also know that even if you survive a year, it won’t all be good time. Eventually, perhaps even in a few months, your mental function will begin to deteriorate. You will begin to lose your memory and have trouble with even the simplest of thoughts. And, it isn’t clear that any treatment will delay this. Perhaps treatment may not be your best choice. That is something you have to decide for yourself.

“As a U.S. Senator, you need to decide how effective you can be. In a short time, you will need to step down. You may not even know when this begins to happen and might even need someone to tell you – if they have the nerve to do so.

“Dying with a glioblastoma is not painful. What happens is the brain just begins to shut down and you lose contact with the outside world. Eventually, the shut-down becomes complete and bodily functions stop. It isn’t a bad way to die, because you really won’t be aware. But it isn’t what anyone wants for themselves and you will need constant help and support.

“If anyone you designate, in addition to your family wants to talk to me, please have them call me. And of course, feel free to call anytime.”

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